First Edition
| Card Name | The Isaac of Isaac: Re-Isaac |
| Type | Room Deck |
| Card Text | Each character is named Isaac, and each item has “ ↷ : Choose a dice roll. Itscontroller rerolls it” and eternal and loses all other abilities. “Isaac was simple, and they were both Isaac.” |
| Game Mode(s) | All Game Modes |
| Set | Warp Zones  |
| Released | 2022 |
| Language(s) | English, French, German, Italian, Spanish |
| Background Artist | Yazawa Akio |
| Card Artist | Nikola Rakonjac |
Ruling – This card does not copy the recharge effect of the D6, only the reroll effect.