The Binding of Isaac: Four Souls

A complete reference for The Binding of Isaac: Four Souls card game.

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Room Deck

Everything Must Go

Black Market

The Isaac of Isaac: Re-Isaac

White Champions

The Mirror

Tax for the Mighty

Static Shock

Spoils of War

Splash Damage

Spider Webs

Social Goals!

Shell Game

Shadow of War

Shadow of Famine

Samson’s Blessing

Restock Machine

Red Vise

Red Champions

Planetarium

Pity for the Poor

Might for the Meek

Maggy’s Blessing

Laser Eye!

Key Master

Isaac’s Blessing

I Am Error

Heavy is the Head

Haunted!

Gus

Greed Looms

Fortune Teller

Floor Spikes

Eternal Chest

Equality

Eden’s Blessing

Dice Room!!!!!!

Dice Room!!!!!

Dice Room!!!!

Dice Room!!!

Dice Room!!

Dice Room!

Devil Beggar

Conjoined Twin

Challenge Room

Butter Fingers

Bum-bo is Loose!

Bomb Beggar

Blood Money

Blood Lust

Blood Donation

Blind Rage

Blessing of the Sack

Blessing of the Inner Eye

Blessing of Steam

Blessing of Greed

Black Champions

Battle Royale!!!!!

Battle Royale!!!

Angelic Intervention

All Hallows Eve

Slot Machine

Blessing of Gluttony

Beggar

Battle Royale!!!!

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Latest Updates

G FUEL Promo Cards!
The Binding of Isaac is collaborating with G FUEL to release an exclusive collector’s box which will include two limited-edition… Continue reading G FUEL Promo Cards!
Trick or Treat Challenge
Maestro Media has announced the latest Four Souls challenge, Trick or Treat via tweet today. To access the PDF, visit Maestro… Continue reading Trick or Treat Challenge
Lord of the Flies Challenge
Maestro Media has announced the latest Four Souls challenge, Lord of the Flies, via tweet today. To access the PDF,… Continue reading Lord of the Flies Challenge

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The Binding of Isaac: Four Souls is ™ & © 2025 Edmund McMillen and Maestro Media