First Edition
| Card Name | The Lost |
| Type | Characters |
| Card Text |  1 |  1 Play an additionalloot card this turn. At the end of your turn, recharge up to 1 character. Starting Item:  Holy Mantle  |
| Starting Item |  |
| Game Mode(s) | All Game Modes |
| Set | The Unboxing of Isaac  |
| Released | 2023 |
| Language(s) | English |
| Card Artist | Edmund McMillen |
The Lost, along with Cain and Isaac, was a free, exclusive bonus for those who purchased an entire year of The Unboxing of Isaac subscription service. The 13th box was given to both annual and monthly subscribers, as long as no boxes were skipped.
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