First Edition
| Card Name | Seraphim |
| Type | Treasure Deck |
| Card Text | You have +1 to the 1st, 3rd, and 5th attack roll you make each turn. “Above it stood the seraphims: Each one had six wings; with twain he covered his face, and with twain he covered his feet, and with twain he did fly.” Isaiah 6:2 |
| Category | Passive Items |
| Game Mode(s) | All Game Modes |
| Set | The Unboxing of Isaac  |
| Released | 2022 |
| Language(s) | English |
| Background Artist | TikaratheMew |
| Card Artist | Yazawa Akio |
Seraphim, along with Eden’s Soul and The Stairway, was exclusive to The Unboxing of Isaac subscription service for August 2022 (The Ascent Box).