The Binding of Isaac: Four Souls

A complete reference for The Binding of Isaac: Four Souls card game.

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Alternate Art

Monstro

The Beast

Delirium

Mega Fatty

XVII. The Stars (en)

Lost Soul

XIII. Death

Guppy’s Paw

Brimstone

Godhead

The Dark One

Twitchy

The Lamb

Mom!

It Lives!

Big Bony

Devil Deal

Little Horn

Larry Jr.

Mom’s Hand

Pin

Ultra Greed!

Daddy Long Legs

Rag Man

Hornfel

Clotty

Dingle

Gaper

Gurdy

Secret Room!

Fistula

Mega Satan!

Pestilence

Min Min

Shop Upgrade!

Satan!

Mulliboom

Brownie

Polycephalus

Monstro II

Rag Mega

The Bloat

The Duke of Flies

Famine

Ambush!

Begotten

Mulligan

The Capricious

The Forgotten

Azazel

Isaac

Eden

Eden

Lilith

The Lost

The Harlot

The Keeper

Blue Baby

The Savage

Judas

Guppy

Mega Satan!

Epic Fetus!

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Latest Updates

G FUEL Promo Cards!
The Binding of Isaac is collaborating with G FUEL to release an exclusive collector’s box which will include two limited-edition… Continue reading G FUEL Promo Cards!
Trick or Treat Challenge
Maestro Media has announced the latest Four Souls challenge, Trick or Treat via tweet today. To access the PDF, visit Maestro… Continue reading Trick or Treat Challenge
Lord of the Flies Challenge
Maestro Media has announced the latest Four Souls challenge, Lord of the Flies, via tweet today. To access the PDF,… Continue reading Lord of the Flies Challenge

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The Binding of Isaac: Four Souls is ™ & © 2025 Edmund McMillen and Maestro Media