The Binding of Isaac: Four Souls

A complete reference for The Binding of Isaac: Four Souls card game.

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Paid Items

Mystery Gift

Magic Mushroom

Tumor Ball

A Dollar!

A Quarter!

Isaac’s Tears

Satanic Bible

Keeper’s Sack

The Jar

Sacrificial Dagger

Hallowed Ground

Battery Pack

The Crowdfunder

Spewer

Ser Junkan

Athame

Succubus

Dad’s Key

Smelter

Portable Slot Machine

Golden Razor Blade

Pay to Play

Battery Bum

Donation Machine

Contract From Below

The Poop

Tech X

Red Proglottid

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Latest Updates

G FUEL Promo Cards!
The Binding of Isaac is collaborating with G FUEL to release an exclusive collector’s box which will include two limited-edition… Continue reading G FUEL Promo Cards!
Trick or Treat Challenge
Maestro Media has announced the latest Four Souls challenge, Trick or Treat via tweet today. To access the PDF, visit Maestro… Continue reading Trick or Treat Challenge
Lord of the Flies Challenge
Maestro Media has announced the latest Four Souls challenge, Lord of the Flies, via tweet today. To access the PDF,… Continue reading Lord of the Flies Challenge

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The Binding of Isaac: Four Souls is ™ & © 2025 Edmund McMillen and Maestro Media