The Binding of Isaac: Four Souls

A complete reference for The Binding of Isaac: Four Souls card game.

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Summer of Isaac

Pestilence

Holy Greed

Found Soul

Shopkeeper

Recycling Sticker

Everything Must Go

Magic Mushroom

Charmed Vis

Tainted Mulligan

Karma

Isaac’s Last Will

Mulligoon

Mega Bean!

Conjoined D6

Giant Poop

Curse of Envy

Telekinesis

Era Walk

Mugger Bean!

Hot Potato!

Cursed Haunt

MOTHER!

The Bloat

The Adversary

Gemini

Hush

The Miser

Krampus

Conjoined Fatty

Conquest

The Hoarder

Widow

Headless Horseman

The Rainmaker

War

Dogma

Coil

Tumor Ball

The Monster

Ball of Tar

Gish

Cereus Peashy

Light Switch

A Friend

Club

Clubby the Seal

Police Lineup

Weltling

Unstable DNA

Stacy

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Latest Updates

G FUEL Promo Cards!
The Binding of Isaac is collaborating with G FUEL to release an exclusive collector’s box which will include two limited-edition… Continue reading G FUEL Promo Cards!
Trick or Treat Challenge
Maestro Media has announced the latest Four Souls challenge, Trick or Treat via tweet today. To access the PDF, visit Maestro… Continue reading Trick or Treat Challenge
Lord of the Flies Challenge
Maestro Media has announced the latest Four Souls challenge, Lord of the Flies, via tweet today. To access the PDF,… Continue reading Lord of the Flies Challenge

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The Binding of Isaac: Four Souls is ™ & © 2025 Edmund McMillen and Maestro Media